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KMID : 0378119930200010193
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Chungnam Medical Journal
1993 Volume.20 No. 1 p.193 ~ p.202
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Intraocular Pressure Changes with Thiopental Sodium Propofol, and Midazolam
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Abstract
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Intraocular pressure(IOP) were measured during induction of anesthesia with thiopental sodium(n=10), propofol(n=10), and midazolam(n=10).
IOP were measured using a Schioetz tonometer before and after induction, and 1min and 3min after endotracheal intubation.
All patients were divided into three groups as follows;
Group I(n=10): thiopental sodium 5mg/kg was administered intravenously for induction of anesthesia
Group II(n=10): propofol 2mg/kg was administered intravenously for induction of anesthesia
Group III(n=10): midazolam 0.2mg/kg was administered intravenously for induction of anesthesia
Succinylcholine 1mg/kg were administered intravenously for endotracheal intubation in all groups.
@ES The results were as follows:
@EN 1) Induction of anesthesia with propofol and thiopental sodium are associated with a significant reduction in IOP.
2) Induction of anesthesia wit propofol is associated with more significant reduction in IOP than thiopental sodium.
3) Induction of anesthesia with midazolam is not associated with reduction in IOP.
From above results, propofol can be used as effectively as thiopental sodium for general anesthesia in patients who undergo ophthalmic surgery.
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